高原环境下皮肤微生物群对皮肤病影响的研究进展

Research progress in the effects of skin microbiota on skin diseases in plateau environments

摘要:

高原特殊环境下，机体皮肤会出现一系列适应性反应和病理性变化，这些变化包括皮肤屏障功能受损、皮肤血管收缩障碍、角质层异常增厚、纤维素沉积等，导致高原地区皮肤疾病的发病率相对较高。研究表明，高原环境中皮肤微生物的组成和多样性会发生变化，这可能与皮肤疾病的发生、发展密切相关。本文旨在综述高原环境对皮肤的影响、高原常见皮肤病，以及微生物对皮肤疾病的影响，并探讨高原环境下皮肤微生物群对皮肤疾病的影响及作用机制。

关键词:皮肤微生物;皮肤疾病;高原环境

Abstract:

In the special environment of plateau, adaptive responses and pathological changes occur in the skin of organisms, which include skin barrier dysfunction, skin vasoconstriction disorder, abnormal thickening of the stratum corneum, and fibrous pigment deposition, leading to a high incidence of skin diseases in plateau areas. In the plateau environment, the composition and diversity of skin microbiota change, which may be related to the occurrence and development of skin diseases. This paper reviews the effects of plateau environments on the skin, common skin diseases in plateau environments, and the effects of skin microbiota on skin diseases and discusses the mechanisms by which skin microbiota influences skin diseases in plateau environments.

Key words:skin microbiota;skin diseases;plateau environment