解析细菌免疫系统

Analysis of bacterial immune system—A review

摘要:

摘要:在细菌与噬菌体之间的生存斗争中，细菌面临噬菌体的威胁，进化了多种免疫机制。在这些免疫机制中，有的采用被动适应，有的采用主动防御的策略，阻止噬菌体DNA 进入细胞，裂解侵入的DNA，或以宿主细胞死亡的方式，阻止噬菌体的扩散。各种机制的相互配合，在细菌细胞中构成了一个有效的免疫系统。本文在综述细菌免疫系统最新研究进展基础上，重点分析讨论了细菌免疫系统的作用模式，以及细菌免疫系统与噬菌体之间的进化关系。

Abstract:

Abstract:In the battle to phages，bacteria have evolved many immune mechanisms involved in the prevention of phage DNA entry，the degradation of entered DNA，and the limitation of the phage spreading at the cost of host cell death. An immune system in bacteria is formed by the collaboration of multiple immune mechanisms． In this paper，we reviewed the latest research progress of bacterial immune system and focused on the analysis of the operation mode of bacterial immune system and the evolution relationship between this system and phages．