细菌荚膜多糖

Bacterial capsular polysaccharide—A review

摘要:

摘要:随着分子生物学、糖化学和免疫学的发展，细菌荚膜多糖的研究逐步深入。不仅对其特性及组成有了进一步的了解，而且对其多糖合成相关基因、合成调节和致病性进行了更为细致的研究。本文概括了细菌荚膜多糖的化学结构、合成相关基因、多样性产生机制、合成调节、功能与致病性和应用前景，总结其研究热点，以期为荚膜多糖的研究和应用提供理论依据和思路。

Abstract:

Abstract:The study on bacterial capsular polysaccharide is deeper with the development of the molecular biology，saccharide chemistry and immunology． Not only the character and structure of bacterial capsular polysaccharide was researched，but also the genes related to the synthesis，regulation and pathogenicity． This review focuses on the chemical structure，synthesis genes，mechanisms of the diversity，synthesis regulation，function，pathogenicity and application of the bacterial capsular polysaccharide． The research hot spots are also summarized to supply the basic theory and threads to study and apply bacterial capsular polysaccharide．