原核生物中土霉味化合物二甲萘烷醇和2-甲基异茨醇生物合成研究进展

Biosynthesis of geosmin and 2-methylisoborneol in the prokaryotes—A review

摘要:

摘要:由原核生物蓝藻和放线菌引起的水体土霉异味问题备受世界的关注。本文以土霉味化合物二甲萘烷醇和2-甲基异茨醇的研究历史为主线，综述了土霉味化合物二甲萘烷醇和2-甲基异茨醇的化学特性、生物合成途径以及生物合成相关基因和酶等方面的研究进展，探讨了土霉味化合物二甲萘烷醇和2-甲基异茨醇生物合成研究的重要意义，并展望了土霉味化合物二甲萘烷醇和2-甲基异茨醇生物合成研究存在的问题及发展的方向。

Abstract:

Abstract:The occurrence of off-flavor problems caused by prokaryotes cyanobacteria and actinomycetes is a worldwidewater and food quality issue． Based on literatures on two earthy-muddy-smelling metabolites，(i.e.,geosmin and 2-methylisoborneol (2-MIB))，we reviewed their chemical characteristics，biosynthetic pathways，genes and enzymes that are involved in biosynthesis． Then we discussed current research questions related to off-flavor and future directions．Finally，we addressed the significance of probable key regulatory mechanism for the production and release of geosmin and 2-MIB，which could provide more scientific strategies to better control off-flavors outbreaks in drinking and aquaculture water．