细菌Ⅵ型分泌系统的研究进展

Advances in bacterial type Ⅵ secretion system－A review

摘要:

摘要：Ⅵ型分泌系统（Type Ⅵ secretion system，T6SS）是最近发现的一种新的分泌系统，广泛存在于革兰氏阴性菌变形菌门细菌中，主要由构成分泌系统的结构蛋白、形成跨膜管道结构的转位蛋白、分泌蛋白以及一些对分泌系统起辅助功能的蛋白组成。T6SS能够增强细菌对外界环境的适应性，介导细菌对宿主细胞的致病力以及其他功能。

关键词:关键字：Ⅵ型分泌系统，结构，功能，调控

Abstract:

Abstract: Type Ⅵ secretion system (T6SS) is a newly found secretion system, which distributes widely in Gram-negative bacteria. It consists of structural proteins (constitute secretion system), translocated proteins (form transmembrane pipe structure), secretory proteins and a few auxiliary function proteins for secretion systems. T6SS can enhance the adaptability of bacteria on the environment, mediate pathogenicity to host cells and has some other functions.

Key words:Keywords: Type Ⅵ secretion system, structure, function, regulation