布洛芬微生物降解研究进展

Recent advances in microbial degradation of ibuprofen - A review

摘要:

摘要：布洛芬是苯丙酸类非甾体类抗炎药物的典型代表，属于重要的药物及个人护理品类物质。大量生产和广泛使用的布洛芬在为人类减轻病痛的同时，也带来诸多环境污染危害，已经成为重要潜在环境污染物之一。本文简要介绍布洛芬的使用情况和环境中布洛芬残留的潜在风险，重点总结布洛芬的微生物降解及降解机理研究，提出应当关注污水、脱水污泥、河流沉积物和湿地中布洛芬的微生物降解，强调开展布洛芬降解基因克隆和功能分析以及从分子水平阐明布洛芬降解机理研究的必要性及紧迫性。

Abstract:

Abstract: Ibuprofen has been recognized as an environmental endocrine disruptor due to its ability to interfere with prostaglandin synthesis. In order to address the myriad challenges faced by the issue of ibuprofen in the environment, the recent research progress was summarized in this paper to characterize the ibuprofen consumption, its potential hazard, and biodegradation and degradation mechanisms. The importance and urgency to carry out the ibuprofen degradable gene cloning, its function analysis and its molecular degradation mechanisms were emphasized.