工业微生物菌种改造的新方法———优势小基因组生产菌的构建

New method for industrial microbial strains improvement———construction of dominant genomesimplified strains—A review

摘要:

摘要:本文介绍了构建优势小基因组生产菌株的必要性和可行性;介绍了优势小基因组工业微生物的构建原理和方法;同时，还介绍了几个目前已成功应用的通过基因组精简提高生产效率的例证;最后，结合作者的研究对优势小基因组生产菌的应用进行了展望。

Abstract:

Abstract:The necessity and feasibility of constructing dominant genome-simplified strains for industrial production were introduced，based on some successful cases in which the production efficiency was improved after simplifying the genome of strains． The principle and process of genome simplifying were summarized． In addition，the perspective of dominant genome-simplified strains for industrial production was discussed，combined with authors' own studies.