微生物内分泌学:揭示微生物与激素相互作用对感染的影响机制

Microbial endocrinology: impact of interactions between microbes and neuroendocrine hormones on infection—A review

摘要:

摘要:微生物内分泌学是一门将微生物学、神经生理学和内分泌学等学科结合在一起形成的交叉学科。本文以儿茶酚胺类激素作用于细菌为例，介绍了此类激素对细菌的作用机制，特别是促进细菌生长以及增强细菌对宿主细胞的吸附和侵染能力的机制，而且对激素与细菌作用的受体及与细菌群居效应的相关性进行了简要介绍。该学科的提出不但有助于深入认识细菌与宿主的相互作用，而且对畜牧生产中的健康养殖和动物性食品安全均具有重要指导意义。

Abstract:

Abstract:Microbial endocrinology is a crossdisciplinary field representing the intersection of microbiology with mammalian endocrinology and neurophysiology． In this review，effects of catecholamine on bacteria were used as an example to demonstrate the interactions between microbes and neuroendocrine hormones．Catecholamine modulates bacterial infectivity by stimulation of bacteria growth and augmentation of host tissue attachment and invasion．Moreover，the bacterial adrenergic receptors recognized by catecholamine and its relationship with quorum sensing signals were also addressed．This review will be helpful for understanding the interactions between microorganism and host as well as health breeding and food safety in animal industries．