大肠杆菌α-溶血素分泌途径研究进展

Advance on Escherichia coli α-hemolysin secretion pathway—A review

摘要:

摘要:随着生物技术的不断发展，大肠杆菌胞外分泌分子机理日渐明晰，大肠杆菌表达系统成为实现规模化制备胞外重组蛋白的途径之一。本文综述了大肠杆菌α-溶血素分泌途径的转运机制及应用前景。

Abstract:

Abstract:In recent years，with the development of biotechnology，the molecular mechanism of the secretion pathways in Escherichia coli is clearer and clearer，and it becomes one of the most effective methods to use E.coli expression system for extracellular production of recombinant proteins． This review discusses recent advances in the secretion mechanism and application of E.coli α-hemolysin secretion pathway．