人苍白杆菌研究进展

Research progress of Ochrobactrum anthropic-A review

摘要:

摘要:人苍白杆菌是一种革兰氏阴性杆菌，通常被认为是一种条件致病菌，其感染多与机体全身或局部免疫低下有关，主要引起菌血症、脑膜炎、化脓性感染等疾病。近年，随着感染范围的扩大和病例数的增加，目前已成为人类常见的病原菌。由于其临床表现多样化、耐药性较广以及与某些病原有交叉凝集等特点，致使预防和临床诊疗变得较为复杂。就人苍白杆菌的生物学特性、鉴别诊断、免疫性、耐药性及基因组特征等研究进展予以概述，为该病的预防、控制和诊疗管理提供参考。

Abstract:

Abstract:Ochrobactrum anthropi is a gram-negative bacillus，usually known as an opportunistic pathogen． Mostly its infection is related with systemic or local lower immunity，and manifested as bacteremia，meningitis，purulent infection．Recently，along with expanded infection，it has become an important human pathogen．The prevention，clinical diagnose and treatment become complicated because varied clinical symptoms increased antibiotic resistance and cross immune reaction with others pathogens． In this review，we summarized the biological characteristics，differential diagnosis，immunity，resistance and genomic characteristics of Ochrobactrum anthropi，to provide reference for prevention，control and treatment management of this disease．