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首页 > 过刊浏览>2016年第56卷第5期 >740-746. DOI:10.13343/j.cnki.wsxb.20150305
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传染性法氏囊病病毒的自然重组
作者:
基金项目:

国家自然科学基金重点项目(31430087);黑龙江省自然科学基金(QC2015037);哈尔滨市应用技术研究与开发基金(2014AB3AN058);哈尔滨市创新人才研究专项资金(2014RPQYJ129)


Naturally occurring reassortants of infectious bursal disease virus-A review
Author:
  • Xiaole Qi

    Xiaole Qi

    Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Harbin 150001, Heilongjiang Province, China
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  • Li Gao

    Li Gao

    Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Harbin 150001, Heilongjiang Province, China
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  • Xiaomei Wang

    Xiaomei Wang

    Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Harbin 150001, Heilongjiang Province, China;Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, Jiangsu Province, China
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  • 摘要
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    摘要:

    传染性法氏囊病病毒(Infectious Bursal Disease Virus, IBDV)是双RNA病毒科(Birnaviridae)的典型代表,其引起的传染性法氏囊病(Infectious Bursal Disease, IBD)是危害养禽业的一种重要免疫抑制病和致死性传染病。IBDV的自然重组给疫病防控带来了新风险。本文综述了IBDV基因组节段重组和基因内重组的主要类型,分析了其形成机制及生物学意义,提出了该类病毒遗传演化研究以及疫病综合防控的新思路。

    Abstract:

    Infectious bursal disease virus (IBDV) is an important representative of Birnaviridae, which causes infectious bursal disease (IBD), one important immuno-suppressive and fatal disease threatening the poultry husbandry. The naturally occurring reassortants of IBDV induced new risks to disease prevention and control. Here, we reviewed the main types of the genome segments reassortants and intragenic recombination, the inherent mechanism and the biological significances were analyzed, which would give us new insights into the virus genetic evolution research and the disease control strategy.

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祁小乐,高立,王笑梅. 传染性法氏囊病病毒的自然重组[J]. 微生物学报, 2016, 56(5): 740-746

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  • 收稿日期:2015-07-11
  • 最后修改日期:2015-08-21
  • 在线发布日期: 2016-05-06
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