细菌趋化信号通路中的磷酸酯酶CheZ

Advances in phosphatase CheZ of bacterial chemotaxis signaling pathway

摘要:

摘要:细菌通过趋化系统获得在复杂环境中的生存优势。趋化性在细菌致病性、病菌定殖、固氮细菌与宿主共生、植物与微生物互作等方面有重要的作用。作为趋化信号适应中不可或缺的调节蛋白，对CheZ的深入研究具有重要意义。本文主要对CheZ的结构、作用机制、功能调节、蛋白定位以及进化地位等方面的研究现状进行了综述，旨在为其它细菌中趋化系统的研究提供有益参考。

关键词:关键词:趋化系统，磷酸酯酶，CheZ，蛋白定位

Abstract:

Abstract:Bacteria get a survival advantages in the complex environment through the chemotaxis system. Chemotaxis plays an important role in colonization and pathogenicity of bacteria, the legume–rhizobia symbiosis, and plant-microbe interactions. Phosphatase CheZ is an indispensable regulatory protein in the process of chemotactic signal adaptation. This review focused on the structure, mechanism of action, functional regulation, protein targeting and the status of the evolutionary of CheZ. This work can benefit the study of other bacterial chemotaxis systems.

Key words:Keywords: chemotaxis system, phosphatase, CheZ, protein targeting