环境雌激素的微生物降解

Microbial degradation of environmental estrogens

摘要:

雌激素作为环境内分泌干扰物的一类重要物质，生物降解法是最为经济、最为绿色和最为适用的去除方法。通过分析雌激素的主要来源和危害、国内外雌激素降解菌的筛选与鉴定、类固醇雌激素降解酶的表达与检测、雌激素降解菌的基因组学特征以及雌激素的降解途径和机制，进一步阐述了雌激素生物降解的研究现状与进展，对未来的研究工作作出了展望。

Abstract:

Estrogens are major substances of environmental endocrine disruptors, and biodegradation is the most economical, greenest and most suitable method to remove them. We elaborated the research status and progress of estrogen biodegradation by analyzing the major sources and hazards of estrogen, the isolation and identification of estrogen-degrading bacteria, the expression and detection of steroidal estrogen-degrading enzymes, the genomics study of estrogen-degrading bacteria and the estrogen degradation pathways. We also address future works of biodegradation of environmental estrogens.