鸭疫里默氏杆菌毒力及耐药机制研究进展

Research advances in the virulence and antibiotics resistance mechanism of Riemerella anatipestifer

摘要:

鸭疫里默氏杆菌（Riemerella anatipestifer，RA）是引起鸭浆膜炎的一种革兰氏阴性病原菌，属黄杆菌科。该菌自发现以来，在我国各养鸭地区时有暴发和流行，具有多种血清型及对多种抗生素耐药的特点，给我国养鸭业的健康发展造成严重威胁。近年来，随着分子生物学及相关技术的发展，越来越多的科研工作人员对鸭疫里默氏杆菌的毒力、耐药及耐药机制等方面进行了研究并取得了一定的进展。本文将针对以上研究结果进行总结和评述，以期为进一步深入研究该菌及有效防控该菌引起的疾病带来启示与借鉴。

关键词:鸭疫里默氏杆菌;毒力基因;铁利用;耐药机制

Abstract:

Riemerella anatipestifer is a Gram-negative bacterium causing serositis in ducks and belongs to Flavobacteriaceae. Since its discovery, its outbreak and epidemic happen from time to time in various duck industries of China. Furthermore, it has a variety of serotypes and resistance to multiple antibiotics, leading to a serious threat to the duck industries. In recent years, with the help of molecular biology and related new technologies, more and more researchers have studied the virulence, antibiotics resistance and antibiotics resistance mechanism. Our review summarizes the above research progress, provide enlightenment and reference for further understanding this bacterium to prevent this disease.

Key words:Riemerella anatipestifer;virulence genes;use of iron;resistance mechanism