霍乱弧菌检测技术研究进展

Advances in detection of Vibrio cholerae infection

摘要:

随着社会的发展，公共卫生及水体质量已得到明显提升，但到目前为止在发展中国家由霍乱疫情导致的死亡率依旧非常高，而霍乱弧菌即为霍乱疫情爆发的病原菌，且霍乱在我国被列为甲类传染病。目前国内外针对霍乱弧菌已经建立了多种有效的检测技术，对控制霍乱暴发作用显著。本文综述了近年来霍乱弧菌检测技术研究新进展，包括微生物学、免疫学、分子生物学等较成熟的检测方法，生物传感器、快速检测技术等新兴检测方法，并总结各种技术优缺点，展望未来霍乱弧菌检测的市场需求。

关键词:霍乱弧菌;检测;RDT;生物传感器

Abstract:

Nowadays, global water quality has been improved significantly with the development of public health. However, the death rate caused by cholera epidemic is still high in developing countries. Vibrio cholerae, the exact pathogen for the cholera epidemic, has been categorized as a Class A infectious disease in China. At present, a series of effective detection techniques for Vibrio cholerae have been established worldwide. In this study, recent advances on detection technology of Vibrio cholerae, including microbiology immunology, molecular biology, biosensors and rapid detection technology methods, were summarized. In addition, the advantages and disadvantages of various technology were compared, and the market demand of vibrio cholerae detection in the future was addressed.

Key words:Vibrio cholerae;detection;RDT;biosensor