酵母内源性海藻糖代谢调控研究进展

Advances in regulation of endogenous trehalose metabolism in yeast

摘要:

作为一种天然稳定剂的双糖，海藻糖（Trehalose）在逆境下对生物体活性的保护功能既吸引了广泛的研究兴趣，也使其具有良好的应用价值和潜力。本文聚焦重要模式微生物和工业应用微生物酵母，结合组学研究最新进展，从海藻糖代谢途径、应激条件下的海藻糖代谢和转录特征以及提高胞内海藻糖含量策略等方面，对内源性海藻糖研究新进展进行了综述。

Abstract:

As a naturally stable disaccharide, the protective function of trehalose on the activity of organisms under adverse conditions has attracted a wide range of research interests, and also has good application value and potential. This paper focuses on the important model microorganisms and industrial applied yeast, combined with the latest progress in the research of omics, and summarizes the new progress in the research of endogenous trehalose from the aspects of trehalose metabolic pathway, trehalose metabolism and transcription characteristics under stress conditions, and the strategy of improving intracellular trehalose.