Aureobasidium spp. are cosmopolitan yeast-like fungi and popularly known as black yeasts due to their melanin production. Many strains of Aureobasidium spp. are found to secreted extracellular lipids as liamocins. Liamocins are surface active and has promising anticancer and antibacterial activities. This paper reviewed the variety of liamocin-secreting Aureobasidium spp. and the factors that affecting liamocins production. It also summarized the research progress of the biosynthetic pathway of liamocins. Also some further research of liamocins production by Aureobasidium spp. was recommended.