微生物产色素机制及其生物活性

Production mechanism and biological activity of microbial pigments

摘要:

近年来,随着人工合成色素的大量使用引起一系列环境和健康问题,增加了人们对安全、无毒天然色素的需求。天然色素主要来源于植物和微生物,由于植物生长周期较长使植物源色素在大规模应用中受限。与植物源天然色素相比,微生物源色素易于大规模快速培养,具有更广阔的应用前景。本文系统总结了不同微生物源色素产生机制,及其在抗菌、抗氧化及抗癌等生物医药领域的研究进展,并对其面临的问题及未来的发展进行了展望。

Abstract:

The environmental and health problems caused by the massive use of synthetic pigments in recent years increase the demand for safe,non-toxic natural pigments.Natural pigments are mainly derived from plants and microorganisms.However,the large-scale application of plant-derived pigments is limited by the long growth cycle of plants.Compared with plants,microorganisms are easy to be cultivated on a large scale in a short time and thus microorganism-derived pigments have a broad application prospect.We systematically summarized the production mechanisms,reviewed the research progress in the antibacterial,anti-oxidation and anti-cancer activities,and put forward the opportunities and challenges in the development of microorganism-derived pigments.