植物相关细菌中Ⅵ型分泌系统的功能研究进展

Research progress in the function of type VI secretion system in plant-associated bacteria

摘要:

Ⅵ型分泌系统(type VI secretion system, T6SS)是一种强大的细菌分子武器，它通过将效应蛋白注入原核或真核细胞而介导细菌间竞争并影响宿主的生命活动。T6SS广泛分布于革兰氏阴性菌中，主要存在于变形菌门(Proteobacteria)。尽管T6SS的研究大多集中在动物相关细菌上，但它在植物相关细菌中的作用不能被忽视。本文对植物相关细菌的T6SS进行了较为详细的介绍，主要从T6SS的发现、T6SS在植物相关细菌间竞争中的作用、在细菌与植物互作中的作用以及在植物生物防治中的作用等4个方面综述了最新的研究成果，旨在为今后更好地研究植物相关细菌T6SS的生物学功能及其应用提供指导。

关键词:Ⅵ型分泌系统(T6SS);植物相关细菌;功能;效应蛋白;生物防治

Abstract:

The type VI secretion system (T6SS), a powerful tool of bacteria, is involved in inter-bacterial competition and affects host life activities by injecting effector proteins into prokaryotic or eukaryotic cells. T6SS is ubiquitous in Gram-negative bacteria, mainly existing in Proteobacteria. Although most studies of T6SS have focused on animal bacteria, its role in plant-associated bacteria cannot be ignored. We introduced the T6SS of plant-associated bacteria in detail and summarized the latest research achievements from four aspects: the discovery of T6SS, the role of T6SS in the competition among plant-associated bacteria, the role of T6SS in the interactions between bacteria and plants, and the role of T6SS in the biocontrol of plant diseases. This review aims to provide guidance for the future research on the biological functions and applications of T6SS in plant-associated bacteria.

Key words:type VI secretion system (T6SS);plant-associated bacteria;function;effector;biocontrol