2025年6月13日 周五
首页 > 过刊浏览>2023年第63卷第10期 >3955-3966. DOI:10.13343/j.cnki.wsxb.20230136
PDF HTML阅读 XML下载 导出引用 引用提醒
2017–2022年中国口蹄疫流行状况分析
作者:
基金项目:

国家重点研发计划（2021YFD1800300）


Epidemiological characteristics of foot-and-mouth disease in China between 2017 and 2022
Author:
  • 摘要
    • | |
  • 访问统计
    • |
  • 参考文献 [23]
    • |
  • 相似文献 [20]
    • | | |
  • 文章评论
    摘要:

    【目的】分析近年来中国口蹄疫流行和传播特点，研判口蹄疫流行趋势。【方法】以2017-2022年间中国报告发生的口蹄疫疫情为研究对象，从疫情的“三间分布”、生产环节分布、流行毒株分子流行病学分析及溯源等方面，对近6年的疫情情况进行系统梳理。【结果】2017-2022年间中国共有15个省份报告发生口蹄疫疫情54次。总体形势稳定：Asia 1型口蹄疫维持无疫状态；2019-2022年连续4年未发生A型口蹄疫疫情；田间以散发O型口蹄疫为主。六年间报告牛口蹄疫疫情36次，羊疫情1次，猪疫情17次。分子流行病学研究表明，O/Mya-98、O/Ind-2001、O/CATHAY、O/PanAsia和A/Sea-97这5个流行毒株同时流行，且与同时期周边国家（缅甸、老挝和越南等）口蹄疫毒株遗传关系密切。流行病学调查结果显示，疫情（尤其是牛疫情，占比66.7%）主要发生在流通（57%）、散养（32%）等免疫薄弱环节。【结论】对内强化疫苗免疫和流通动物管控，对外严防境外毒株传入仍是今后中国口蹄疫防控的重要任务。

    Abstract:

    [Objective] To reveal the epidemic state and transmission characteristics of foot-and-mouth disease (FMD) in China based on the data of FMD outbreaks during 2017-2022. [Methods] The spatial, temporal, and susceptible species distribution, the production chain distribution, and the molecular epidemiology and traceability of the epidemic strains in China were analyzed.[Results] A total of 54 FMD outbreaks were reported in 15 provinces between 2017 and 2022. The general situation of FMD in China was stable considering the zero outbreak of serotype Asia 1, no report of serotype A for consecutive four years (2019-2022), and sporadic occurrence of serotype O. During 2017-2022, 36 outbreaks of FMD were reported in cattle, one outbreak in sheep, and 17 outbreaks in pigs. There were five epidemic strains (O/Mya-98, O/Ind-2001, O/CATHAY, O/PanAsia, and A/Sea-97) simultaneously circulating in China, which were closely related to the FMDV strains in surrounding countries (e.g., Myanmar, Laos, and Vietnam) during this period. Epidemiological investigation suggested that the outbreaks (especially in cattle, which accounted for 66.7%) mainly occurred in long-distance transport (57%) and backyard (32%) with incomplete vaccination. [Conclusion] In the future, strengthening vaccination and preventing the introduction of foreign strains are still major measures for FMD prevention and control in China.

    参考文献
    [1] KITCHING P, HAMMOND J, JEGGO M, CHARLESTON B, PATON D, RODRIGUEZ L, HECKERT R. Global FMD control:is it an option?[J]. Vaccine, 2007, 25(30):5660-5664.
    [2] JAMAL SM, BELSHAM GJ. Foot-and-mouth disease:past, present and future[J]. Veterinary Research, 2013, 44(1):116.
    [3] SARRY M, ROMEY A, LEFEBVRE D, BENFRID S, DUFOUR B, DURAND B, ZANELLA G, de REGGE N, ZIENTARA S, BAKKALI KASSIMI L, BLAISE-BOISSEAU S. Foot and mouth disease virus:transmission, pathogenesis, diagnosis and surveillance[J]. Virologie (Montrouge, France), 2022, 26(5):355-373.
    [4] BELSHAM GJ. Translation and replication of FMDV RNA[J]. Current Topics in Microbiology and Immunology, 2005, 288:43-70.
    [5] BRITO BP, RODRIGUEZ LL, HAMMOND JM, PINTO J, PEREZ AM. Review of the global distribution of foot-and-mouth disease virus from 2007 to 2014[J]. Transboundary and Emerging Diseases, 2017, 64(2):316-332.
    [6] JAMAL SM, BELSHAM GJ. Molecular epidemiology, evolution and phylogeny of foot-and-mouth disease virus[J]. Infection, Genetics and Evolution:Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2018, 59:84-98.
    [7] RWEYEMAMU M, ROEDER P, MACKAY D, SUMPTION K, BROWNLIE J, LEFORBAN Y, VALARCHER JF, KNOWLES NJ, SARAIVA V. Epidemiological patterns of foot-and-mouth disease worldwide[J]. Transboundary and Emerging Diseases, 2008, 55(1):57-72.
    [8] BLACKSELL SD, SIENGSANAN-LAMONT J, KAMOLSIRIPICHAIPORN S, GLEESON LJ, WINDSOR PA. A history of FMD research and control programmes in Southeast Asia:lessons from the past informing the future[J]. Epidemiology and Infection, 2019, 147:e171.
    [9] 何继军, 靳野, 马维民, 杨亚民, 吕律, 郑海学, 杨帆, 曹伟军, 郭建宏, 李彦敏, 刘在新, 刘湘涛. 外来口蹄疫流行毒株跟踪分析与防控[J]. 中国动物检疫, 2018, 35(11):52-55, 61. HE JJ, JIN Y, MA WM, YANG YM, Lü Lü, ZHENG HX, YANG F, CAO WJ, GUO JH, LI YM, LIU ZX, LIU XT. Tracking analysis and control strategies for exotic FMD epidemic strains[J]. China Animal Health Inspection, 2018, 35(11):52-55, 61(in Chinese).
    [10] SIRDAR MM, FOSGATE GT, BLIGNAUT B, MAMPANE LR, RIKHOTSO OB, PLESSIS B, GUMMOW B. Spatial distribution of foot-and-mouth disease (FMD) outbreaks in South Africa (2005-2016)[J]. Tropical Animal Health and Production, 2021, 53(3):1-12.
    [11] ZHANG Q, LI D, LIU XT, LIU ZX, CAI XP, WU GH, QI SY, YANG SZ, YAN XM, SHANG YJ, HE JJ, MA JW, LI J, MA WM, HAN RC, LIU XL, ZHANG J, XIE QG, ZHANG ZD. Experimental studies with foot-and-mouth disease virus type Asia-1, responsible for the 2005 epidemic in China[J]. Research in Veterinary Science, 2008, 85(2):368-371.
    [12] PATON DJ, di NARDO A, KNOWLES NJ, WADSWORTH J, PITUCO EM, COSIVI O, RIVERA AM, KASSIMI LB, BROCCHI E, de CLERCQ K, CARRILLO C, MAREE FF, SINGH RK, VOSLOO W, PARK MK, SUMPTION KJ, LUDI AB, KING DP. The history of foot-and-mouth disease virus serotype C:the first known extinct serotype?[J]. Virus Evolution, 2021, 7(1):veab009.
    [13] 刘文, 彭勇刚. 湖北省江陵县一起牛口蹄疫疫情的紧急流行病学调查[J]. 中国动物检疫, 2021, 38(5):13-18. LIU W, PENG YG. Emergency epidemiological investigation on an outbreak of cattle FMD in Jiangling County of Hubei Province[J]. China Animal Health Inspection, 2021, 38(5):13-18(in Chinese).
    [14] LEE HS, LEE NH, SEO MG, KO YJ, KIM B, LEE JB, KIM JS, PARK S, SHIN YK. Serological responses after vaccination of growing pigs with foot-and-mouth disease trivalent (type O, A and Asia1) vaccine[J]. Veterinary Microbiology, 2013, 164(3/4):239-245.
    [15] KNOWLES NJ, HE JJ, SHANG YJ, WADSWORTH J, VALDAZO-GONZÁLEZ B, ONOSATO H, FUKAI K, MORIOKA K, YOSHIDA K, CHO IS, KIM SM, PARK JH, LEE KN, LUK G, BORISOV V, SCHERBAKOV A, TIMINA A, BOLD D, NGUYEN T, PATON DJ, et al. Southeast Asian foot-and-mouth disease viruses in Eastern Asia[J]. Emerging Infectious Diseases, 2012, 18(3):499-501.
    [16] 何继军, 杨亚民, 马维民, 尚佑军, 吕律, 郑海学, 靳野, 郭建宏, 刘在新. 我国O型Mya-98口蹄疫病毒流行情况与毒株分析[J]. 中国动物检疫, 2014, 31(5):45-51. HE JJ, YANG YM, MA WM, SHANG YJ, LV L, ZHENG HX, JIN Y, GUO JH, LIU ZX. Epidemic situation and characterization of O/Mya-98 strain of foot and mouth disease virus in China[J]. China Animal Health Inspection, 2014, 31(5):45-51(in Chinese).
    [17] DAVIES G. The foot and mouth disease (FMD) epidemic in the United Kingdom 2001[J]. Comparative Immunology, Microbiology and Infectious Diseases, 2002, 25(5-6):331-343.
    [18] QIU Y, ABILA R, RODTIAN P, KING DP, KNOWLES NJ, NGO LT, LE VT, KHOUNSY S, BOUNMA P, LWIN S, VERIN BC, WIDDERS P. Emergence of an exotic strain of serotype O foot-and-mouth disease virus O/ME-SA/Ind-2001d in South-East Asia in 2015[J]. Transboundary and Emerging Diseases, 2018, 65(1):e104-e112.
    [19] WRLFMD. Molecular Epidemiology/Genotyping Reports. The OIE/FAO world reference laboratory for foot-and mouth disease[R]. 2020.
    [20] PARIDA S. Vaccination against foot-and-mouth disease virus:strategies and effectiveness[J]. Expert Review of Vaccines, 2009, 8(3):347-365.
    [21] TUNCER-GÖKTUNA P, ÇOKÇALIŞKAN C, ARSLAN A, TAŞÇENE N, UZUN EA, GÜNDÜZALP C, BALCı GN, KARA O, GÜLYAZ V. Monitoring the performance of foot-and-mouth disease vaccines prepared against local strains in the face of antigenic evolution in the field[J]. Transboundary and Emerging Diseases, 2021, 68(2):648-655.
    [22] BELSHAM GJ. Towards improvements in foot-and-mouth disease vaccine performance[J]. Acta Veterinaria Scandinavica, 2020, 62(1):1-12.
    [23] MAHAPATRA M, PARIDA S. Foot and mouth disease vaccine strain selection:current approaches and future perspectives[J]. Expert Review of Vaccines, 2018, 17(7):577-591.
    引证文献
    网友评论
    网友评论
    分享到微博
    发 布
引用本文

何继军,马维民,吕律,靳野,杨亚民,杨帆,曹伟军,刘永杰,吴锦艳,张向乐,朱紫祥,郭建宏,刘在新,刘湘涛,郑海学. 2017–2022年中国口蹄疫流行状况分析[J]. 微生物学报, 2023, 63(10): 3955-3966

复制
分享
文章指标
  • 点击次数:583
  • 下载次数: 923
  • HTML阅读次数: 851
  • 引用次数: 0
历史
  • 收稿日期:2023-03-05
  • 最后修改日期:2023-06-12
  • 在线发布日期: 2023-10-09
  • 出版日期: 2023-10-04
文章二维码

科微学术

微生物学报

您是本站第 6084612 访问者

通信地址：北京市朝阳区北辰西路1号院3号 中国科学院微生物研究所   邮编：100101

电话：010-64807516    E-mail：actamicro@im.ac.cn

版权所有：微生物学报 ® 2025 版权所有