菌毛可视化及其在蓝细菌研究中的应用

Visualization of pili and its applications in the study of cyanobacteria

摘要:

蓝细菌是海洋水圈的重要成员，同时作为海洋生物活性化合物的重要来源而备受关注。IV型菌毛(type IV pili, TFP)在蓝细菌中至关重要，参与多种生理功能，包括介质表面运动、趋光行为和自然转化等过程。随着菌毛可视化技术的不断进步，对这些微生物的TFP相关细胞行为有了更深入的了解。本文以菌毛可视化为切入点，总结了该技术在蓝细菌蹭行运动、趋光、自然转化等研究领域的最新研究和应用，本文旨在促进对蓝细菌中TFP介导的细胞行为的理解，以及蓝细菌在水圈中的生态学功能及意义，同时也为发展基于TFP的蓝细菌行为调控提供新思路。

Abstract:

Cyanobacteria have garnered great attention as important players in the marine hydrosphere and the source of bioactive compounds. Type IV pili (TFP) play a crucial role in cyanobacteria by participating in various physiological functions such as substrate surface movement, phototaxis, and natural transformation. With the continuous advancements in the visualization of pili, we have gained a deeper understanding of the TFP-mediated cell behaviors of cyanobacteria. We review the recent progress and applications of visualization of pili in the research on the twitching, phototaxis, and natural transformation of cyanobacteria. This review is expected to improve our understanding of the TFP-mediated cell behaviors and the ecological function and significance of cyanobacteria in the hydrosphere. Additionally, it provides new insights for developing TFP-based regulation on cell behaviors of cyanobacteria.