细菌中钙信号的作用

An update of calcium signaling in bacteria A review

摘要:

摘要：越来越多的实验证明二价钙离子（Ca2+）在细菌中有重要调控作用。本文从Ca2+ 信号对细菌生理的影响、细胞内Ca2+ 浓度及测定方法、细菌中Ca2+ 的运输和Ca2+ 结合蛋白四个方面综述了目前细菌中钙信号的研究进展。

关键词:关键词：钙信号;细菌;自由钙离子浓度;调控

Abstract:

Abstract: In eukaryotes, Ca2+ is an important second messenger and regulates diverse cellular activities ranging from muscle contraction to fertilization. In bacteria, growing evidence suggests that Ca2+ also plays important regulatory roles in various physiological processes. Here we review current understanding of calcium regulation in bacteria from the following aspects: 1） the concept of bacterial [Ca2+]i and its determination; 2）cellular processes affected by [Ca2+]i changes; 3）transportation of Ca2+ across bacterial membrane; 4）eukaryotic calcium binding proteins in bacteria and their functions.

Key words:Keywords: calcium signaling; bacteria; [Ca2+]i; regulation