(1. The National Engineering Center for Research of Microbial Pharmaceuticals, Yunnan Institute of Microbiology, Yunnan University, Kunming 650091) (2. Leibniz-Institut für Meereswissenschaften, IFM-GEOMAR, Düsternbrooker Weg 20, D-24105 Kiel, Germany) 在期刊界中查找 在百度中查找 在本站中查找
The National Engineering Center for Research of Microbial Pharmaceuticals, Yunnan Institute of Microbiology, Yunnan University, Kunming 650091 在期刊界中查找 在百度中查找 在本站中查找
The National Engineering Center for Research of Microbial Pharmaceuticals, Yunnan Institute of Microbiology, Yunnan University, Kunming 650091 在期刊界中查找 在百度中查找 在本站中查找
Development of antibiotics from actinomycetes has acquired enormous accomplishment. About 12000 bioactive metabolites were discovered from actinomycetes. Up to now it is very difficult to finding novel compounds with bioactivities from microorganisms. Advance of discovery of new actinomycete species from extreme environments and ocean, integration of modern chemical techniques and database, and genomic techniques are reviewed for meeting the challenge and difficulty in pharmaceutical development from actinomycetes in this paper.
