后基因组时代微生物遗传学教学的探讨

Tips and ideas for the teaching of Microbial Genetics in the post-genome era

摘要:

对后基因组时代“微生物遗传学”课程教学进行探讨。提出以故事化课堂和形象化讲解增加学生的学习乐趣。为了更好地帮助学生理解后基因组学方法, 将后基因组学与微生物遗传学融合教学(包括正向遗传学方法与快速正向遗传学方法、单基因敲除和表型分析与全基因组规模基因敲除和表型分析、传统的遗传相互作用与全基因组的遗传相互作用融合讲授)。此外, 生物信息学网络资源的介绍延伸了课堂教学并提高了课堂教学质量。

关键词:微生物遗传学, 后基因组学, 生物信息学数据库, 故事化课堂, 形象化讲解, 教学质量

Abstract:

In this article, I share my teaching experiences, and explore ideas on teaching Microbial Genetics in the post-genome era. To increase student interest in this course, I propose the use of story-telling and visualization as two teaching strategies. In addition, to help students better understand post-genomic approaches, I suggest integration of traditional genetics and related post-genomics (examples of integration include traditional forward genetics and fast forward genetics, phenotypic analysis of single-gene deletion and genome-wide deletion mutant analysis, and traditional genetic interactions and genome-wide genetic interactions). Also, introducing online bioinformatics resources extends the classroom teaching, and improves teaching quality.

Key words:Microbial Genetics, Post-genomics, Bioinformatics databases, storytelling in teaching, visualized teaching, Teaching quality