科微学术
微生物学通报
2025年8月8日 周五
省产学研重大专项项目(No. 2010N5009); 福建省自然科学基金项目(No. 2012J01137); 福建省教育厅科研基金项目(No. JA11152)
CAI Hui-Nong
1. College of Bioengineering, Jimei University, Xiamen, Fujian 361021, China 2. Research Center of Food Microbiology and Enzyme Engineering Technology (Jimei University), Fujian Province, Xiamen, Fujian 361021, China 3. Research Center of Food Biotechnology of Xiamen City, Xiamen, Fujian 361021, ChinaNI Hui
1. College of Bioengineering, Jimei University, Xiamen, Fujian 361021, China 2. Research Center of Food Microbiology and Enzyme Engineering Technology (Jimei University), Fujian Province, Xiamen, Fujian 361021, China 3. Research Center of Food Biotechnology of Xiamen City, Xiamen, Fujian 361021, ChinaSU Wen-Jin
1. College of Bioengineering, Jimei University, Xiamen, Fujian 361021, China 2. Research Center of Food Microbiology and Enzyme Engineering Technology (Jimei University), Fujian Province, Xiamen, Fujian 361021, China 3. Research Center of Food Biotechnology of Xiamen City, Xiamen, Fujian 361021, China法夫酵母能合成一种具有很高商业价值的类胡萝卜素——虾青素。它广泛应用于饲料、保健品、医药、化妆品等行业。探索法夫酵母中虾青素合成途径及其调控机理对天然虾青素资源的开发具有重要的意义。虽然许多学者通过各种方法对该途径进行了一系列的研究, 但其机理目前尚未完全阐明。本文综述了法夫酵母虾青素合成途径以及合成途径中相关基因的研究进展, 并对基于基因调控的产量提高策略进行了讨论, 为利用基因工程技术进行定向育种提供了思路。
The Phaf?a rhodozyma has found commercial application as natural source of astaxanthin, a known antioxidant with large importance in the aquaculture, pharmaceutical, and food industries. To satisfy the growing demand for astaxanthin, there are strong efforts to develop economically viable bioprocesses alternative to the current chemical synthesis. However, up to now, natural astaxanthin from P. rhodozyma has not been cost competitive with chemically synthesized astaxanthin, and the knowledge about the carotenogenesis regulation is still limited in comparison to other carotenogenic fungi. The aim of this short review is to examine the published studies concerning the biosynthetic pathway of astaxanthin and the related genes in P. rhodozyma, and describe their applications to improve the bioprocess of astaxanthin production. It also mentions some gaps and opportunities in this field that should be addressed or exploited in the near future.
李天丽,蔡慧农,李利君,倪辉,苏文金. 法夫酵母虾青素合成途径相关基因的研究进展[J]. 微生物学通报, 2013, 40(9): 1673-1685
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