Advances in detection methods for Streptococcus suis

Abstract:

Streptococcus suis, a major pathogen of pigs, can cause meningitis, septicemia, and arthritis, leading to serious economic losses in the pig industry. In addition, it can also infect humans and result in diseases or death, being a zoonotic pathogen. Therefore, accurate, rapid, sensitive, and simple detection methods are critical for the prevention and control of swine streptococcosis. At present, a variety of detection methods for S. suis have been developed, including traditional detection methods of microbiology, molecular biology, and immunology and emerging technologies such as nanomaterial-based immunosensors, CRISPR-Cas12a system, and matrix-assisted laser desorption ionization-time of flight mass spectrometry. This review summarizes the principles, applications, advantages, and disadvantages of the above methods and introduces the future directions of S. suis detection methods, aiming to provide reference for the prevention and control of swine streptococcosis.

Key words:Streptococcus suis;immunological assay;molecular biological detection method;CRISPR-Cas12a;immunosensor