Occurrence and mechanism of ferroptosis in livestock and poultry diseases

doi:10.13343/j.cnki.wsxb.20240540

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Occurrence and mechanism of ferroptosis in livestock and poultry diseases
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                        10.13343/j.cnki.wsxb.20240540
                    
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                        LEI DiLEI Di
Joint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China;Chongqing Collaborative Innovation Research Institute, National Center of Technology Innovation for Pigs, Chongqing 402460, China
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XU BoyiXU Boyi
Joint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China;Chongqing Collaborative Innovation Research Institute, National Center of Technology Innovation for Pigs, Chongqing 402460, China
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FANG RendongFANG Rendong
Joint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China;Chongqing Collaborative Innovation Research Institute, National Center of Technology Innovation for Pigs, Chongqing 402460, China
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WANG HongzhiWANG Hongzhi
Joint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China;Chongqing Collaborative Innovation Research Institute, National Center of Technology Innovation for Pigs, Chongqing 402460, China
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Abstract:

Ferroptosis is a novel form of programmed cell death that is iron-dependent and primarily characterized by lipid peroxidation. Studies have indicated that ferroptosis is closely related to the occurrence and development of various diseases. A variety of pathogens have been confirmed to induce ferroptosis of host cells, which facilitates pathogen proliferation and counteracting host immunity. Therefore, ferroptosis extensively participates in the pathophysiological processes caused by pathogen infection. In addition, ferroptosis is involved in the pathological process of many metabolic and poisoning diseases. This paper reviews the research progress in the occurrence and mechanism of ferroptosis in livestock and poultry diseases, aiming to provide reference for further exploring the effect and mechanism of ferroptosis in livestock and poultry diseases.

Key words:ferroptosis;livestock and poultry diseases;host cell;pathogenesis

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LEI Di, XU Boyi, FANG Rendong, WANG Hongzhi. Occurrence and mechanism of ferroptosis in livestock and poultry diseases. [J]. Acta Microbiologica Sinica, 2025, 65(1): 52-61

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Received:September 01,2024
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