Research progress in the effects of skin microbiota on skin diseases in plateau environments
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1.College of Pharmacy, Qinghai Minzu University, Xining, Qinghai, China;2.Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

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This work was supported by the Second Affiliated Hospital of Soochow University Pre-research Fund (SDFEYBS2308) and the Second Affiliated Hospital of Soochow University Discipline Building Project (XKTJ-XK202406).

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    Abstract:

    In the special environment of plateau, adaptive responses and pathological changes occur in the skin of organisms, which include skin barrier dysfunction, skin vasoconstriction disorder, abnormal thickening of the stratum corneum, and fibrous pigment deposition, leading to a high incidence of skin diseases in plateau areas. In the plateau environment, the composition and diversity of skin microbiota change, which may be related to the occurrence and development of skin diseases. This paper reviews the effects of plateau environments on the skin, common skin diseases in plateau environments, and the effects of skin microbiota on skin diseases and discusses the mechanisms by which skin microbiota influences skin diseases in plateau environments.

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BAI Xue, YANG Jianxin. Research progress in the effects of skin microbiota on skin diseases in plateau environments. [J]. Acta Microbiologica Sinica, 2025, 65(3): 968-980

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  • Received:November 06,2024
  • Online: March 10,2025
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