Ping Yu
College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, ChinaHaisen Sun
College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, ChinaJianrong Li
College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, ChinaXiaohui Wang
College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, ChinaHaixia Lu
College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, ChinaSupported by the Key Program for the Development of Functional Food in the National Science & Technology Pillar Program during the 11th Five-year Plan Project (2006BAD27B03)
Abstract: [Objective] To explore the mechanism of cholesterol-degrading by Lactobacillus plantarum LpT1 and LpT2 in vitro. [Methods] After Lactobacillus plantarum LpT1 and LpT2 being inoculated and cultured in the medium MRS, MRS+CH, MRS+CH+S and MRS+CH+N, the cholesterol content in supernatant, deposit and cells, and the total cholesterol content before and after inoculation were determined and compared to primarily predict the mechanism of cholesterol-degrading by L. plantarum. [Results] The mechanism of cholesterol- degrading by L. plantarum LpT1 and LpT2 in vitro involved in metabolic and non-metabolic pathway. Non-metabolic pathway was related to co-precipitation and cell absorption. Metabolic pathway was due to the production of the special enzymes during the growth of L. plantarum which made the cholesterol degrade to be other materials and caused its content reduction. [Conclusion] L. plantarum has shown its ability to degrade cholesterol in vitro.
Ping Yu, Haisen Sun, Jianrong Li, Xiaohui Wang, Haixia Lu. Cholesterol-degrading by Lactobacillus plantarum LpT1 and LpT2 in vitro. [J]. Acta Microbiologica Sinica, 2011, 51(4): 561-565
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