Advance on Escherichia coli α-hemolysin secretion pathway—A review

Home > Archive>Volume 53, Issue 10, 2013 >1011-1017

Advance on Escherichia coli α-hemolysin secretion pathway—A review
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                        Lingqia SuLingqia Su
State Key Laboratory of Food Science and Technology，School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education，Jiangnan University，Wuxi 214122，China
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Sheng ChenSheng Chen
State Key Laboratory of Food Science and Technology，School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education，Jiangnan University，Wuxi 214122，China
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Jing WuJing Wu
State Key Laboratory of Food Science and Technology，School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education，Jiangnan University，Wuxi 214122，China
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Fund Project:Supported by the National Natural Science Foundation of China (31100048)，by the Science and Technology Support Project of Jiangsu Province (BE2012018，BE2012019) and by the Research and Innovation Project for College Graduates of Jiangsu Province (Lingqia，Su)

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Abstract:

Abstract:In recent years，with the development of biotechnology，the molecular mechanism of the secretion pathways in Escherichia coli is clearer and clearer，and it becomes one of the most effective methods to use E.coli expression system for extracellular production of recombinant proteins． This review discusses recent advances in the secretion mechanism and application of E.coli α-hemolysin secretion pathway．

Key words:Keywords: Escherichia coli，α-hemolysin secretion pathway，extracellular expression，recombinant protein

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Lingqia Su, Sheng Chen, Jing Wu. Advance on Escherichia coli α-hemolysin secretion pathway—A review. [J]. Acta Microbiologica Sinica, 2013, 53(10): 1011-1017

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Received:March 03,2013
Revised:June 05,2013
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Online: September 29,2013
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