Intestinal defense system and mechanism of maintenance of microbiota homeostasis in insects

doi:10.13343/j.cnki.wsxb.20170375

Home > Archive>Volume 58, Issue 6, 2018 >1036-1048. DOI:10.13343/j.cnki.wsxb.20170375

Intestinal defense system and mechanism of maintenance of microbiota homeostasis in insects
DOI:
                        10.13343/j.cnki.wsxb.20170375
                    
CSTR:
                        32112.14.j.AMS.20170375
                    
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                        Zhichao YaoZhichao Yao
Institute of Urban and Horticultural Entomology, College of Plant Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei Province, China
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Shuai BaiShuai Bai
Institute of Urban and Horticultural Entomology, College of Plant Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei Province, China
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Hongyu ZhangHongyu Zhang
Institute of Urban and Horticultural Entomology, College of Plant Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei Province, China
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In the long-term evolution process, insects have formed a unique intestinal defense system. The combination of physical barrier and the immune system resists invasive microbes. Alike most metazoans, the guts of insects are in permanent contact with the microbial realm that includes beneficial symbionts, food-borne microbes and life-threatening pathogens. Thus, gut epithelium can tolerate a certain amount of commensal microbes proliferation for the beneficial gut-microbe interactions, accompanied by the proficient elimination of detrimental microbes. Based on the function of Duox-ROS system and immune deficiency pathway in the intestinal immune response, these immune systems are involved in the regulation of gut microbiota homeostasis. In this article, we reviewed recent advances in insect intestinal defense mechanisms, combined with the intestinal immune signaling pathways and the regulation mechanism of intestinal immune system on the gut microbiota homeostasis.

Key words:intestinal microbiota;peritrophic matrix;intestinal immunity;Duox-ROS immune system;Imd signaling pathway

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Zhichao Yao, Shuai Bai, Hongyu Zhang. Intestinal defense system and mechanism of maintenance of microbiota homeostasis in insects. [J]. Acta Microbiologica Sinica, 2018, 58(6): 1036-1048

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Received:July 27,2017
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