Advances in interactions between gut microbiota and mitochondria

doi:10.13343/j.cnki.wsxb.20180198

Home > Archive>Volume 58, Issue 11, 2018 >1908-1915. DOI:10.13343/j.cnki.wsxb.20180198

Advances in interactions between gut microbiota and mitochondria
DOI:
                        10.13343/j.cnki.wsxb.20180198
                    
CSTR:
                        32112.14.j.AMS.20180198
                    
Author:
                        Xiawei ZhangXiawei Zhang
National Center for International Research on Animal Gut Nutrition, Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China
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Chunlong MuChunlong Mu
National Center for International Research on Animal Gut Nutrition, Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China
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Weiyun ZhuWeiyun Zhu
National Center for International Research on Animal Gut Nutrition, Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China
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Abstract:

The relationship between gut microbiota and mitochondria is very close. On the one hand, intestinal microorganisms can directly or indirectly through the digestion of nutrients in food to produce metabolites such as short-chain fatty acids, hydrogen sulfide and nitric oxide, affect the energy metabolism process associated with mitochondria, regulate mitochondrial reactive oxygen species production, and regulate mitochondria and even the entire body's immune response. On the other hand, intestinal cell mitochondrial dysfunction and mitochondrial genome genetic variation also affect the composition and function of the gut microbiota. In this paper, we summarized recent advances in the relationship between gut microbiota and mitochondria. It provides a theoretical basis for targeting the intestinal flora and mitochondria to regulate intestinal health.

Key words:gut microbiota;mitochondria;energy metabolism;reactive oxygen;immunity

Reference

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Xiawei Zhang, Chunlong Mu, Weiyun Zhu. Advances in interactions between gut microbiota and mitochondria. [J]. Acta Microbiologica Sinica, 2018, 58(11): 1908-1915

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Received:April 29,2018
Revised:July 11,2018
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Online: November 06,2018
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