Progress in research on quorum sensing and intestinal biofilm formation of Lactobacillus

Abstract:

The intestine is a complicated microenvironment and hosts a large and complex flora of microorganisms, which plays an important role in host gut health. Quorum sensing is an important mechanism of information transmission among bacteria through chemical signal molecules. This article reviews the composition of quorum sensing system, signal transduction mechanism and the regulation of intestinal biofilm formation by AI-2/LuxS quorum sensing system. This review introduces the lactic acid bacteria AI-2/LuxS quorum sensing system and its role in the regulation of biofilm formation in intestine. The review will evoke new ideas for renovation of intestinal barrier function and intestinal health regulation.

Key words:intestine;quorum sensing;biofilm;Lactobacillus