Research progress on signal pathways of different diarrhea-causing Escherichia coli infections

Abstract:

Diarrhea Escherichia coli is one of the main pathogens causing human and animal diseases in the world, and brings great losses to the social economy. According to different pathogenic mechanisms, diarrhea Escherichia coli can be divided into six types:enteropathogenic E. coli, enterohemorrhagic E. coli, enteragglutinative E. coli, enterotoxigenic E. coli, diffusion adhesive E. coli and enteroinvasive E. coli. Different pathogenic E. coli invades the host in different ways and causes different inflammatory reactions. In this paper, the differences of inflammatory signal pathways caused by different pathogenic E. coli were analyzed, and the relationship between inflammatory signal pathways and pathogenic infection, prevention and treatment were discussed. The paper aims to lay a foundation for the study of pathogenic mechanism and treatment of diarrhea E. coli.

Key words:diarrhea Escherichia coli;virulence factors;inflammation;signaling pathway