Biofilm-associated drug resistance in Streptococcus suis

Abstract:

Streptococcus suis is a human-zoonotic infectious disease that seriously affects the pig industry and human health in various countries. It can cause septicemia, arthritis, meningitis and other diseases, thus causing huge economic losses. The biofilm formation is the main cause of increasing pathogenicity and drug resistance of S. suis. It is of great significance to understand and master the biofilm formation and drug resistance mechanism of S. suis, and to find the effective method of removing biofilm for the prevention and treatment of S. suis. This review updates the latest scientific knowledge about the formation and drug resistance mechanism of S. suis biofilm, focusing on biochemical factors, physiological factors, molecular mechanism and environmental changes, etc., to summarize and discuss the drug resistance mechanism of S. suis biofilm, to provide a scientific theoretical basis for the prevention and treatment of the disease.

Key words:Streptococcus suis;biofilm;antibiotic resistance;drug resistance mechanisms