Chinese medicine against Candida albicans

Abstract:

Fungal infections (mycoses) have been on the rise and fungal pathogens have gradually developed drug resistance amid the long-term use of conventional antifungal drugs such as fluconazole. Chinese medicine is superior in anti-fungal infection. Our research group has been carrying out systematic and in-depth research on the in vivo and in vitro effects and mechanisms of antifungal Chinese medicine with the support of a number of national and provincial projects. Therefore, on the basis of the latest research outcomes in Chinese medicine’s anti-fungal infection of our research group and others in China and abroad, we summarize the research on Chinese medicine combating fungi (mainly Candida albicans) in the past five years.

Key words:Chinese medicine;Candida albicans;adhesion;dimorphic switch;biofilms;hydrolytic enzymes;infection