Research progress in metabolites of filamentous fungi against Bursaphelenchus xylophilus

Abstract:

Pine wilt disease caused by Bursaphelenchus xylophilus is a severe disease with strong transmission and destructive damage to the forest ecosystems in China. It is therefore urgent to prevent this disease. Compared with the physical and chemical control measures of B. xylophilus, biocontrol being environmentally friendly has a wide research prospect. Filamentous fungi and their secondary metabolites have less impact on the environment and more specific lethal effects on B. xylophilus than chemical nematicides. Therefore, it is of great significance to isolate antinematodal metabolites from filamentous fungi and determine their structures and activities. This paper introduces the structures and activities of metabolites from filamentous fungi against B. xylophilus. A total of 57 metabolites against B. xylophilus have been discovered in the past two decades, with diverse structures and varied activities. This paper systematically summarizes the structures and activities of all the metabolites to facilitate the research in this field and then summarizes and prospects the research in this field. It is hoped that this review will provide reference for the biocontrol of pine wilt disease and the further research on the metabolites of filamentous fungi against B. xylophilus.