Qingping Wu
Guangdong Institute of Microbiology, Guangzhou 510070, ChinaKui Wu
Guangdong Institute of Microbiology, Guangzhou 510070, ChinaYingyang Ye
Guangdong Institute of Microbiology, Guangzhou 510070, ChinaXiaohui Dong
Guangdong Institute of Microbiology, Guangzhou 510070, ChinaJumei Zhang
Guangdong Institute of Microbiology, Guangzhou 510070, ChinaSupported by the Guangdong Provincial Natural Science Foundation(06201654)
Abstract: Quorum sensing (QS) is a phenomenon that microbes regulate some of their genes by signals related to the density of population. It is confirmed that acyl-homoserine lactones (AHL), some peptides, some furanones and some other small moleculars can be used as quorum-sensing signals by microbes. Microbes control their physiology with different QS systems in parallel or hierarchical ways. A lot of microbial pathogenesis connect with quorum sensing closely. More and more studies show that QS systems regulate in microbial pathogenesis through the following points: (1) QS helping pathogens invasion and colonization; (2) QS regulating production of virulent factor; (3) QS giving pathogens the ability of immunity or drug resistance. We review the role of QS in microbial pathogenesis and address a new way to prevent and control microbial diseases.
Qingping Wu, Kui Wu, Yingyang Ye, Xiaohui Dong, Jumei Zhang. amongAnimal-associated Pathogens-a review. [J]. Acta Microbiologica Sinica, 2009, 49(7): 853-858
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